High resolution

Module 12: Figure schizophrenia

Functional modulation of GABAergic interneurons in schizophrenia

This Figure summarizes some of the signalling mechanisms of the fast-spiking GABAergic interneurons that are thought to be altered in schizophrenia. Some components have reduced activity (yellow arrows), whereas others are increased (red arrows), usually as part of a compensatory mechanism. See the text for further details.