High resolution

Module 12: Figure cardiac contractile elements

Structural organization of the contractile and cytoskeletal elements of cardiac cells.

The asterisks identify proteins that can lead to hypertrophy when they are mutated. Reproduced by permission from Macmillan Publishers Ltd: Nature, Chien, K.R. (2000) Genomic circuits and the integrative biology of cardiac diseases. 407:227–232. Copyright (2000); http://www.nature.com; see Chien 2000.