High resolution

Module 11: Figure TNFα apoptotic signalling

Tumour necrosis factor α (TNFα) activation of the extrinsic apoptotic pathway.

Apoptotic ligands such as tumour necrosis factor α (TNFα) or Fas ligand (FasL) bind to members of the trimeric TNFα receptor family (TNFαR or Fas) to initiate the extrinsic signalling cascade, as described in the text. An animated version of this figure is available.