Cell Signalling Biology
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Please cite as Berridge, M.J. (2011) Cell Signalling Biology; doi:10.1042/csb0001011
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TNFα apoptotic signalling
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Module 11: Figure TNFα apoptotic signalling (animated)
Tumour necrosis factor α (TNFα) activation of the extrinsic apoptotic pathway.
Tumour necrosis factor α (TNFα) binds to three of the TNFα receptors (TNFαRs) to initiate the signalling cascade, as described in the text.

Original figure