High resolution

Module 10: Figure neuronal structure

Organization of the endoplasmic reticulum (ER) in a typical neuron.

Beginning with the soma, the endoplasmic reticulum (ER) (shown in red on the left and coloured pink on the right) is attached to the nuclear membrane and extends outwards to invade all parts of the neuron. Within the soma and proximal dendrites, it comes into close contact with the plasma membrane to form specialized structures known as subsurface cisternae (SSC). The ER extends further up into the dendrites and sends small protuberances into many of the spines. The ER lying within the spine is often referred to as the spine apparatus. On the opposite side of the cell, the ER extends down the axon and into the synaptic ending.