Module 9: Figure SMC proliferation

Role of Ca2+ in the regulation of smooth muscle cell (SMC) contraction and proliferation.

Both contraction and proliferation of smooth muscle cells (SMCs) are regulated by Ca2+. The role of different ion channels in regulating Ca2+ signalling is described in Module 7: Figure smooth muscle cell E-C coupling. High levels of such signalling contribute to both vasoconstriction and proliferation.