Module 9: Figure T cell Ca2+ oscillations

Oscillations in activated T cells.

Response of single human peripheral lymphocytes to phytohaemagglutinin (PHA; open bars) or to PHA plus charybdotoxin (PHA+CTX; closed bar). The traces on the bottom represent the average response from 200 cells. Reproduced from Cell Calcium, Vol. 21, Verheugen, J.A.H., Le Deist, F., Devignot, V. and Korn, H., Enhancement of calcium signaling and proliferation responses in activated human T lymphocytes: inhibitory effects of K+ channel block by charybdotoxin depend on the T cell activation state, pp. 1–17. Copyright (1997), with permission from Elsevier; see Verheugen et al. 1997.