High resolution

Module 8: Figure nodal Ca2+ gradient

A standing Ca2+ gradient in the node of a mouse embryo.

The Ca2+ indicator Fluo3 was used to detect the high level of Ca2+ located in a band of cells on the left (L) side of the node. Reproduced from Cell, Vol. 114, McGrath, J., Somlo, S., Makova, S., Tian, X. and Brueckner, M., Two populations of node monocilia initiate left–right asymmetry in the mouse, pp. 61–73. Copyright (2003), with permission from Elsevier; see McGrath et al. 2003.