Module 8: Figure ZP3-induced Ca2+ signals
Ca2+ signalling events during the sperm acrosome reaction induced by ZP3.
When sperm interacts with the zona pellucida, it binds to ZP3 that initiates the Ca2+ signal, which has three distinct phases as described in the text. Modified from Molecular Biology of the Cell (Mol. Biol. Cell, 2000, 11:1571–1584.) with the permission of The American Society for Cell Biology; see O’Toole et al. 2000.