Module 8: Figure Drosophila planar cell polarity
Functional assay of planar cell polarity in Drosophila.
A. In the wild-type abdomen, all the bristles are orientated in an anterior–posterior direction as illustrated by the yellow arrows. B. A small Frizzled− clone reverses the polarity of cells posterior to the clone (blue arrows). C. A small clone overexpressing Fat (green cells) located in a background of cells deficient in Flamingo. The somewhat haphazard bristle orientation of the Flamingo− cells near the clone is altered so that several layers have their bristles pointing towards the clone both in the anterior and posterior regions (blue arrows). Information contained in Figure 2 from Lawrence et al. (2007) was used to construct this figure.