High resolution

Module 7: Figure ventricular Ca2+ signalling

Summary of Ca2+ signalling in cardiac ventricular cells.

There are a large number of components responsible for Ca2+ signalling in ventricular cells. In addition to activating the periodic contractions of the heart, Ca2+ also contributes to the stimulation of the gene transcription events responsible for remodelling the cardiac signalsome during hypertrophy. The numbers on the figure summarize the main processes of this signalling network that are described in the text.