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Module 7: Figure parietal cell

Parietal cell structure.

The epithelium of the stomach folds into gastric glands that contain mucous neck cells that communicate with the surface, HCl-secreting parietal cells and chief (zymogen) cells that secrete pepsinogen. The apical region of the resting parietal cell (shown on the left of the right-hand panel) contains a large number of vesicles and tubules of variable length. Following stimulation, this tubulovesicular system fuses with the apical membrane to form an extensive canaliculus containing a large number of thin microvilli.