Module 7: Figure mesangial cell
Control of intraglomerular mesangial cell functions.
Intraglomerular mesangial cells respond to a wide range of stimuli to control contraction, proliferation and formation of the extracellular matrix (ECM). See the text for further details. ANF, atrial natriuretic factor; BK, large-conductance K+ channel; cGKI, cyclic GMP-dependent protein kinase I; CLCA, Ca2+-sensitive Cl− channel; NO, nitric oxide; sGC, soluble guanylyl cyclase; VOC, voltage-operated channel.