Module 7: Figure ICC–SMC synchronization



Simultaneous recording of Ca2+ transients in a urethral interstitial cell of Cajal (ICC) and a smooth muscle cell (SMC).

A. The first panel shows the location of an ICC (cell 1) and a smooth muscle cell (cell 2) in a rabbit urethral preparation. The remaining frames taken at 0.2 s intervals illustrate the Ca2+ response of the ICC slightly preceding that of the smooth muscle cell. B. The two traces illustrate the close temporal relationship between the ICC (1) and smooth muscle (2) responses. The Ca2+ transient in the smooth muscle is much briefer than that in the ICC. Reproduced from Hashitani and Suzuki (2007).