High resolution

Module 7: Figure skin cells

Location of skin cells.

The epidermis is composed of multiple layers of differentiating keratinocytes (basal layer, spinous layer, granular layer and stratum corneum). The basal layer invaginates into the hair follicle and contributes to the formation of the sebaceous gland and hair follicle. Epidermal and melanocyte stem cells reside in the bulge region and are used for skin regeneration and repair. During the hair follicle cycle, these two stem cells migrate down into the hair bud where they contribute to the hair matrix that form new hairs during the anagen phase (Module 8: Figure hair follicle cycle).