High resolution

Module 7: Figure salivary gland secretion

Control of fluid and enzyme secretion by the salivary gland.

Acetylcholine acts through the Ca2+ signalling system to increase the ionic fluxes that drive Cl into the lumen with Na+ and water following passively. Noradrenaline (norepinephrine) acts through the cyclic AMP signalling system to stimulate the release of vesicles containing amylase. Cyclic AMP can also potentiate the Ca2+ signalling system by sensitizing the inositol 1,4,5-trisphosphate (InsP3) receptors to the stimulatory action of InsP3. CA, carbonic anhydrase; PKA, protein kinase A.