Module 4: Figure signalsome transcription

Ca2+ regulates the phenotypic expression of the Ca2+ signalsome.

During differentiation, each cell type assembles a specific Ca2+ signalsome, which delivers a Ca2+ transient exactly suited to control its particular cellular responses. In addition, this Ca2+ transient may also contribute to a feedback loop whereby a process of Ca2+-induced transcription of Ca2+ signalling components functions to stabilize the signalsome.