High resolution

Module 4: Figure endosome budding to TGN

Early endosome budding and transport to TGN.

The early endosome receives vesicles from the Golgi carrying proteins such as the cation-independent mannose 6-phosphate receptor (CI-MPR), which is a carrier of various hydrolases. This CI-MPR carrier is then returned to the trans-Golgi network (TGN) once it has been sorted and transferred into vesicles by the mechanism illustrated in this figure.