Please cite as Berridge, M.J. (2011) Cell Signalling Biology; doi:10.1042/csb0001004
The Ca2+-dependent activation of nuclear factor of activated T cells (NFAT).
Module 4: Figure NFAT activation (animated)
An increase in the concentration of cytosolic Ca2+
initiates a series of events that culminate in the transcriptional activation of a large number of genes. [See the text for details of the Ca2+
-dependent activation of nuclear factor of activated T cells (NFAT).]