High resolution

Module 2: Figure PI 3-K family



The regulatory and catalytic subunits of the PtdIns 3-kinase family.

The family of PtdIns 3-kinase is divided into three classes. The kinase domain (shown in yellow) phosphorylates PtdIns4,5P2 (PIP2) to form the lipid messenger PtdIns3,4,5P3 (PIP3). The domain structures of the regulatory and catalytic subunits are described in the text. Information for this figure was taken from Hawkins et al. 2006.