High resolution

Module 2: Figure TGF-βR activation



Activation of the transforming growth factor β (TGF-β) receptor superfamily.

The transforming growth factor β (TGF-β) receptor superfamily uses the Smad signalling pathway to transmit information into the cell. The main features of this pathway can be illustrated by considering the action of TGF-β, which activates the TGF-β receptor complex through a sequential series of reactions as described in the text.