High resolution

Module 1: Figure aldosterone and cortisol biosynthesis

Biosynthesis of mineralocorticoids and corticosteroids.

The mineralocorticoid aldosterone and the corticosteroid cortisol are synthesized from cholesterol through a sequence of reactions driven by a battery of enzymes. The association of the enzymes with either the mitochondrion (green) or the smooth endoplasmic reticulum (ER) (blue) is shown in more detail for aldosterone synthesis in Module 7: Figure glomerulosa cell signalling. See the text for further details.